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Pain in the knees Mauro Keiserman, MD. Rheumatology Specialist by the Brazilian Society of Rheumatology. Head Professor of Rheumatology at the Catholic University School of Medicine (PUC-RS). Arthritis of the knees What are the causes of knee pain? Pain in the knee is extremely frequent. There are several causes. Some are very common and easy to diagnose; there are cases, however, in which elucidating the problem can be a slow, laborious task. In table 1 below are the most frequent diseases.
Table 1 There are two distinct situations concerning pain in the knee. In one of them, a local problem exists, that is, one or more structures that compose the knee show some kind of defect. This can be congenital (patella defects) or appear later, as, for instance, rupture or degeneration of the meniscus. These are orthopedic pathologies and are usually handled by orthopedists. Rheumatologists can intervene in the early stages or when there’s no surgical indication. In the other situation, one or both knees are swollen. Why do the knees swell? When a joint shows swelling, there’s presence of arthritis, which means joint inflammation. Therefore, what we need to know is: why is the knee swollen? But what is inflammation? Is it the same as infection? NO! Inflammation is a response of the organism to an insult aiming at its elimination. Consequently, local warmth, redness (erythema), swelling (edema), and pain develop. A skin cut or laceration causes an inflammation without infection, and the outcome upon healing is a scar. If pus appears in a surgical incision site, it means that bacteria are growing, that is, an infection is present. When the early illness is an infection, the defense mechanism of the organism is an inflammatory response. In this case, the infection leads to inflammation. In table 1, in the diagnoses marked with an asterisk (*), edema will be present only in more advanced stages. That is, patients have “dry” knees. Later, due to local lesions caused by varying unsuitable stimuli inherent to each disease, an inflammatory response develops. In these cases, the joint edema is usually small, in contrast with the pain and restrained function, which may be significant. The syndrome of fatty pad is frequent. It preferentially appears in obese women from age 50. If there’s presence of edema, this is local, with associated bursitis or tendinitis generally occurring (anserine bursitis or tendinitis). Bursae are closed cavities located adjacently to tendons and joints. They can inflame secondarily to tendon inflammation, due to trauma or as a manifestation of some illness, such as gout, when depositions of uric acid crystals cause inflammation. As a rule, knee bursitis is easily noted. The bursae located before or below the patellae can be infected by an infection in the adjacent skin. Tendinitis is addressed in the next chapter. The mechanism characterized as most frequent in the generation of tendinitis is the wear occurring due to continued and strained use of the tendons. There are minute ruptures in the fibers composing the tendons, leading to local inflammatory response and scar tissue formation. The recurrence of this event may cause the tendons to tear up with varying clinical consequences. In the knees, anserine tendinitis is more frequently seen. It’s located in the inner part of the leg and is called so due to the tendons’ anatomic shape attached to this region, which is similar to a goose paw (see annex). It’s a very common cause for a painful non-swollen knee (non-swollen knee periarthritis). A discreet local edema may be present. When there’s intense edema, other causes should be considered, such as gout, rheumatoid arthritis, and infection. Diseases designated with (**) are present in articles on this website’s orthopedy section. Villonodular synovitis is rare. It’s a condition in which there’s a benign outgrowth (it is not cancer) of the synovial membrane. The diagnosis is made through magnetic resonance or biopsy. Osteoarthritis generates joint edema only in its advanced stage. Read more on osteoarthritis in a specific article on this website. knee arthritis
Causes In table 2 below are listed the diseases that most commonly may start with arthritis in one or both knees. This elucidation, however, works as an early orientation. Always Consult with your doctor! Only an expert can advise you with safety. Non-traumatic causes of arthritis (the disease onset may occur with arthritis alone in one knee)
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